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3:04Cleveland Browns Two-Minute Check-In: 11/14/25
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11:29AFC North Midseason Grades
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2:23Cleveland Browns Two-Minute Practice Check-In: 11/13/25
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1:38AFC North Breakdown: Predicting the Browns Record
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2:00Cleveland Browns Two-Minute Practice Check-In: 11/12/25
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2:26Chances That Shedeur Sanders Sees Game Action?
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3:15Week 11 NFL Picks: Seahawks at Rams
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2:42Week 11 NFL Picks: Ravens at Browns
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1:18NFL Playoff Picture: Division No One Wants To Win
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1:14Bryant McFadden: 'You're Not Winning More Games With Dillon Gabriel'
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1:49Is it Time for the Browns to Give Shedeur Sanders an Opportunity?
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10:015 Potential Landing Spots For Kyler Murray
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1:03How the Browns should handle their QB situation
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1:03Ryan Wilson Looks at the Cleveland Browns Potential Draft Strategy
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3:01Cleveland Browns Two-Minute Practice Check-In: 11/7/25
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3:05Cleveland Browns Two-Minute Practice Check-In: 11/6/25
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2:54Cleveland Browns Two-Minute Practice Update: 11/5/25
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2:07Week 10 NFL Picks: Browns at Jets
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2:19Cleveland Browns Two-Minute Practice Check-In: 11/3/25
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1:47Midseason NFL Awards: Defensive Player of the Year
2025 Defensive
| STATS |
CMB
Total Tackles
|
SCK
Sacks
|
FUM
Forced Fumbles
|
INT
Interceptions
|
TD
Interceptions Returned For Touchdown
|
|---|---|---|---|---|---|
| Regular Season | 18 | 1.0 | 1 | 0 | 0 |
Top Isaiah McGuire News
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Browns' Isaiah McGuire: Returns to practice Thursday
McGuire (illness) logged a full practice session Thursday, Daniel Oyefusi of ESPN.com reports.
McGuire missed Wednesday's practice due to an illness, but he was back and able to participate in full one day later. As such, the third-year defensive end should be good to go against the Jets on Sunday.
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Browns' Isaiah McGuire: Under the weather
McGuire did not participate in Wednesday's practice due to an illness, Mary Kay Cabot of The Cleveland Plain Dealer reports.
McGuire is under the weather to start Week 10 prep, but he'll have two more opportunities to return to practice ahead of Sunday's game against the Jets. The third-year defensive end has logged 16 tackles (10 solo), including 1.0 sacks, and one forced fumble through eight regular-season games.
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Browns' Isaiah McGuire: Steps up in Year 2
McGuire racked up 36 tackles (18 solo), including 2.5 sacks, plus three forced fumbles across 16 regular-season appearances with the Browns in 2024.
McGuire ramped up his involvement on defense Year 2, managing to close out the campaign as a clear starter. The 2023 fourth-round pick suited up for just four games as a rookie, but he's now demonstrated a legitimate ability to contribute on defense. He'll spend the offseason looking to further his development in Cleveland's scheme.
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Browns' Isaiah McGuire: Opportunity knocks
McGuire will be given chances on the second team defense after injuries to defensive end Alex Wright (knee) and Isaiah Thomas (knee), Zac Jackson of The Athletic reports.
McGuire, a rookie drafted in the fourth round, lined up with the twos Monday, as did Sam Kamara. The Browns feel good about the top three ends -- Myles Garrett, Za'Darius Smith and Ogbonnia Okoronkwo -- but new defensive coordinator Jim Schwartz planned to utilize a bunch of different pass rushers. Both Thomas and Wright are expected to miss extended time.
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Player Bio
| HT/WT: 6-4, 268 lbs |
| Birthplace: Tulsa, OK |
| Age: 24 |
| School: Missouri |
| Experience: 3 |





















